The following is MEXICANA’s International Network in 1973/74 Winter season, taken from Official Airline Guide Worldwide Edition – Timetable Section – MAR 1974
The unit of the frequencies is weekly, round-trip basis
| Route |
Freq & A/C | REMARK |
| Acapulco – Mexico City – Chicago | 7 727 | |
| Mexico City – Acapulco – Chicago | 2 727 | |
| Mexico City – Cozumel – Miami | 7 727 | |
| Mexico City – Guadalajara – Dallas | 4 727 | |
| Mexico City – Guadalajara – Los Angeles | 3 727 | |
| Mexico City – Guadalajara – Mazatlan – Los Angeles | 7 727 | |
| Mexico City – Guadalajara – Puerto Vallarta – Los Angeles | 5 727 | |
| Mexico City – Guadalajara – San Antonio | 7 727 | |
| Mexico City – Los Angeles | 11 727 | |
| Mexico City – Mazatlan – Denver | 7 727 | |
| Mexico City – Mazatlan – Los Angeles | 2 727 | |
| Mexico City – Merida – Kingston | 1 727 | |
| Mexico City – Merida – San Juan | 3 727 | |
| Mexico City – Monterrey – San Antonio | 7 727 | |
| Mexico City – Puerto Vallarta – Mazatlan – Los Angeles | 2 727 | |
| Mexico City – St. Louis | 3 727 |